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The therapy of Baclofen polyglandular syndrome is a complex task and consists of the treatment of its individual components. The basis of pathogenetic therapy is permanent hormone replacement therapy with functional deficiency of the affected endocrine glands. With adrenal insufficiency, glucocorticoids (hydrocortisone, dexamethasone, prednisolone, triamcinolone), mineralocorticoids (DOXA, deoxycorticosterone trimethylacetate, etc.) are prescribed, and with hypothyroidism - L-thyroxine. With candidiasis accompanying autoimmune polyglandular syndrome type 1, antifungal drugs are used. In diabetes mellitus associated with autoimmune polyglandular syndrome type 2, immunosuppressive therapy with cyclosporine may be required. Patients are advised to use an increased amount of ascorbic acid and salt. It is Baclofen to take alcohol, some drugs. Prognosis of autoimmune polyglandular syndrome.

Early detection of autoimmune polyglandular syndrome and adequate replacement therapy can control the course of the disease. However, the ability to work, as a rule, decreases - patients are assigned II-III disability groups.

Patients with autoimmune polyglandular syndrome are subject to dispensary observation by an endocrinologist and other specialists.

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In stressful conditions, intercurrent infections, physical or mental overstrain, patients need to increase the dose of hormones. It is necessary to immediately consult a doctor in case of any deterioration in well-being. Lethal outcome in autoimmune polyglandular syndrome can occur from laryngospasm, visceral candidiasis, acute adrenal insufficiency.

Diagnosis of autoimmune polyglandular syndrome.

Autoimmune polyendocrine syndromes are an urgent problem of modern medicine, since they include the development of several autoimmune endocrinopathies in the same patient, combined with autoimmune non-endocrine pathology. The review presents a comparative description of four types of autoimmune polyendocrine syndromes, as well as current data on their clinic, diagnosis and treatment.

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Autoimmune polyendocrine syndromes are the actual problem of Baclofen medicine, as include the development of several autoimmune endocrinopathies in the same patient, associated with autoimmune nonendocrine pathology. The review presents a comparative analysis of four types of autoimmune polyendocrine syndromes, as well as current data on their clinical picture, diagnosis and treatment.

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In this case, damage to the mucous membranes of the oral cavity, genitals, as well as skin, nail folds and nails is observed. Before the age of 10, hypoparathyroidism usually develops, which is characterized by neuromuscular hyperacidity.

APS type 1 (APS-1), called APECED (autoimmune polyendocrinopathy, candidiasis, ectodermal-dystrophy) or MEDAC (multiple endocrine deficiency autoimmune candidiasis), is characterized by chronic mucocutaneous candidiasis, chronic hypoparathyroidism, and autoimmune adrenal insufficiency (Addison's disease). , ANN). Most cases of APS type 1 begin in childhood or adolescence. As a rule, its first symptom is mucocutaneous candidiasis, which develops in the first 5 years of life.


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